Dr Chris Della Vedova
|Position:||Program Director: Biosciences|
|Division/Portfolio:||Division of Health Sciences|
|School/Unit:||School of Pharmacy and Medical Sciences|
|Campus:||City East Campus|
|Telephone:||+61 8 830 22267|
|URL for Business Card:||http://people.unisa.edu.au/Chris.DellaVedova|
Dr Chris Della Vedova has a background in genetics with a focus on the genetic and physiological basis for complex neurobehavioural conditions. He received his PhD in Genetics from the University of Missouri (USA) in 2004 and undertook post-doctoral research in evolutionary developmental genetics at the University of Oxford (UK) before joining UniSA as a Lecturer in Biochemistry and Biomedical Sciences in 2008.
- Dr Della Vedova has an interest in teaching genetics, physiology and pathophysiology.
|BIOL 2016||Molecular Genetics|
|BIOL 2056||Physiological Adaptations in Pregnancy|
B.S. in Biology University of Georgia (USA)
Ph.D. in Genetics University of Missouri (USA)
- My research focuses on the molecular and genetic basis of complex neurobehavioural conditions such as addiction, stress and fatigue. Some of my ongoing projects are:
- Identifying biological markers of operator fatigue. In collaboration with the Defence, Science and Technology Organisation and the Centre for Sleep Research at UniSA, we are attempting to identify biological or genetic markers that can detect or predict the deterioration of performance that accompanies fatigue. The identification of such objective tools may help to prevent accidents and loss of life in industrial, medical or military settings.
- Identification of novel genes that play a role in the development of addiction to methamphetamine. Methamphetamine addiction is associated with increased self-reported depression, anxiety and stress levels and a significant risk of drug-induced psychosis. Using a pool of tissue samples collected over several years, we are asking whether variation in a number of candidate genes is associated with an increased risk of drug abuse or dependence, and developing depression, anxiety and/or stress related disorders.
T. M. Guinan, P. Kirkbride, C. B. Della Vedova, S. G. Kershaw, H. Kobus and N. H. Voelcker. 2015. Direct detection of illicit drugs from biological fluids by desorption/ionization mass spectrometry with nanoporous silicon microparticles. Analyst, Advance Article.
Kershaw SG, Della Vedova CB, Majumder I, Ward MB, Farquharson AL, Williamson PA, White JM. Acute opioid administration induce hypothalamic-pituitary-adrenal activation and is mediated by genetic variation in interleukin (IL)1B. Pharmacology, Biochemistry and Behavior. 2015. DOI: 10.1016/j.pbb.2015.09.005
Paech GM, Della Vedova CB, Pajcin M, Grant C, Kamimori GH, Banks S. Caffeine has minimal effects on daytime recovery sleep following severe sleep deprivation. 2016. Sleep & Biological Rhythms 14 (In Press)
Guinan T, Della Vedova C, Kobus H, Voelcker NH. Mass spectrometry imaging of fingerprint sweat on nanostructured silicon. 2015. Chemical Communications. 51 (28): 6088-6091.
Weeks S, Boshoff K, Stewart H, Kelly S, Della Vedova CB. Feasibility of a Research Protocol to Investigate the Effect of the Therapressure ProgramTM Using Salivary Cortisol. 2015. The Open Journal of Occupational Therapy (In Press).
Della Vedova CB, Cathcart S, Dohnalek A, Hutchinson MR, Immink MA, Hayball J. Peripheral interleukin-1beta levels are elevated in chronic tension-type headache patients. 2013. 18 (6): 301-6.
Todd G, Noyes C, Flavel SC, Della Vedova CB, Spyropoulos P, Chatterton B, Berg D, White JM. 2013. Illicit stimulant use is associated with abnormal substantia nigra morphology in humans. PLoS One. 2013;8(2
Cathcart S, Della Vedova C, Immink M, Proeve M, Hayball J. Mindfulness training does not reduce inflammatory cytokine levels in chronic tension-type headache. 2013. Journal of Pain Management 6 (3): 235-238
Cathcart S, Bhullar N, Immink M, Della Vedova C, Hayball J. 2012. Pain sensitivity mediates the relationship between stress and headache intensity in chronic tension-type headache. Pain Res Manag. 2012 Nov-Dec;17(6):377-80.
I am able to provide media comment in the following areas of expertise:
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