Dr Cobus Gerber

I joined the School of Pharmacy and Medical Sciences in 2004 and am involved in the teaching of chemistry courses across various programs. My research activities have focussed on analytical techniques, although organic synthesis and reactivity remains an interest.

• I enjoy contact with students and discovering the obstacles they face with our courses. My interest is to find solutions which address these difficulties.

BSc, Hons, MSc (Port Elizabeth)

PhD (Pretoria)

Dip Ed (Charles Sturt)

• My current interest is trying to understand the chemical composition and behaviour of squid ink components. The ink itself is a complex mixture which goes far beyond providing a simple smoke screen for protection against predators. Although the biology of squid ink is an interest I share with the Melanin Research Group, my focus is on its pharmacological application. Other members of the team include Mike Kokkinn, Frank Madaras and Kristen Brummer.
• Another area of interest is in natural product chemistry. I collaborate with Susan Semple on projects in partnership with Indigenous communities in the Cape Yorke peninsula.
• I also form part of a number of studies looking at the pharmacokinetics of drugs, particularly the development of LC/MS assays.

Oral and i.v. pharmacokinetics of isosteviol in rats as assessed by a new sensitive LC-MS/MS method Hongping Jin, Jacobus P Gerber, Jiping Wang, Min Ji & Andrew K Davey Journal of Pharmaceutical and Biomedical Analysis 48 (2008), pp. 986-990

Jaisue S, Gerber JP, McKinnon R, Davey AK. Effect of E.coli lipopolysaccharide on fexofenadine pharmacokinetics. Drug Metabolism Reviews. 2008. 40(S2). p79.

The disposition of isosteviol in the isolated perfused rat liver. Jin HP, Wang J, Gerber JP, Davey AK. Drug Metabolism Reviews. 2008. 40(S2). p168.

Determination of colistin in human plasma, urine and other biological samples using LC-MS/MS Zheng Ma, Jiping Wang, Jacobus P Gerber & Robert W Milne J. Chrom. B

Determination of isosteviol by LC-MS/MS and its application for evaluating the pharmacokinetics of isosteviol in the rat Maryam Bazargan, Jacobus P Gerber, Jiping Wang, Mohsen Chitsaz, Robert W Milne and Allan M Evans, DARU J. Faculty of Pharmacy Tehran Uni of Med Sciences. 15(3), 2007

Cyclodextrin and modified cyclodextrin complexes of E-4-tert-butylphenyl-4’- oxyazobenzene: UV-visible, 1H NMR and ab initio studies B May, J Gerber, P Clements, M Buntine, D Brittain, S Lincoln and C Easton, Org Biomol Chem, 2005, 3, 1481