Dr Miguel De Barros Lopes

Bachelor of Science, University of Oregon-USA, 1984

Ph.D., University of California-USA, 1991

Selected Publications:

Curtin CD, Bellon JR, Henschke PA, Godden PW, de Barros Lopes MA. (2007) Genetic diversity of Dekkera bruxellensis yeasts isolated from Australian wineries. FEMS Yeast Res. in press.

McBryde C, Gardner JM, de Barros Lopes M, Jiranek V. (2006) Generation of Novel Wine Yeast Strains by Adaptive Evolution, Am. J. Enol. Vitic., 57: 423 - 430.

Cozzolino D, Flood L, Bellon J, Gishen M, De Barros Lopes M.(2006) Combining near infrared spectroscopy and multivariate analysis as a tool to differentiate different strains of Saccharomyces cerevisiae: a metabolomic study. Yeast 30, 1089-96.

Brown SL, Stockdale VJ, Pettolino F, Pocock KF, de Barros Lopes M, Williams PJ, Bacic A, Fincher GB, Hoj PB, Waters EJ. (2006) Reducing haziness in white wine by overexpression of Saccharomyces cerevisiae genes YOL155c and YDR055w. Appl Microbiol Biotechnol. 73, 1363-1376.

de Barros Lopes, M.A. and Ganter F. (2006) Genome Studies of Cactus Yeast. In Plant Genome - Biodiversity and Evolution, A.K. Sharma and A. Sharma eds. (Science Publishers) 459 - 479.

Howell KS, Klein M, Swiegers JH, Hayasaka Y, Elsey GM, Fleet GH, Hoj PB, Pretorius IS, de Barros Lopes MA (2005) Genetic Determinants of Volatile-Thiol Release by Saccharomyces cerevisiae during Wine Fermentation. Applied and Environmental Microbiology. 71: 5420-5426.

Gardner, J.M., McBryde, C., Vystavelova, A., de Barros Lopes M. and Jiranek, V. (2005) Identification of genes affecting glucose catabolism in nitrogen-limited fermentation. FEMS Yeast Research 5: 791-800.

de Barros Lopes MA, Batrowsky EJ, Pretorius IS. The application of gene technology in the wine industry. In Handbook of Food Science, Technology and Engineering (2005)

Pretorius IS, Bartowsky EJ, Bauer FF, de Barros Lopes, MA, du Toit P, van Rensburg P, Vivier MA. The tailoring of designer grapevines and microbial starter strains for a market-directed and quality-focussed wine industry. in Handbook of Food Science, Technology and Engineering - Volume 4 (2005)

Howell, K.S., Swiegers, J.H., Elsey, G.M., Siebert, T.E., Hayasaki, Y., Sefton, M.A., Bartowsky, E.J., Fleet, G.H., Pretorius, I.S. and de Barros Lopes, M. (2004) Variation in 4-mercapto-4-methyl-pentan-2-one release by different wine strains. FEMS Micro Letters 240, 125-129.

Gécz, J., Shaw, M., Bellon, J.R. and de Barros Lopes, M. (2003). Human wild type SEDL protein functionally complements yeast Trs20p, but some naturally occurring SEDL mutants do not. Gene 320, 137-144.

Walker, M.E., Gardner, J.M., Vystavelova, A., McBryde, C.,de Barros Lopes, M. and Jiranek, V. (2003) Application of a reusable, KanMX selectable marker to industrial yeast: construction and evaluation of heterothallic wine strains of Saccharomyces cerevisiae, possessing minimal foreign DNA sequences. FEMS Yeast Research 4, 339-347.

Sutherland, C.M., Henschke, P.A., Langridge, P. and de Barros Lopes, M. (2003) Subunit and cofactor binding of Saccharomyces cerevisiae sulfite reductase. Australian Journal of Grape and Wine Research 9, 186-193.

de Barros Lopes, M., Bellon, J.R., Shirley, N.J. and Ganter, P.F. (2002) Evidence for multiple interspecific hybridisation in Saccharomyces sensu stricto species. FEMS Yeast Research 1, 323-331.

Eglinton, J.M., Heinrich, A.J., Pollnitz, A.P., Langridge, P., Henschke, P.A. and de Barros Lopes, M. (2002) Decreasing acetic acid accumulation by a glycerol overproducing strain of Saccharomyces cerevisiae by deleting the ALD6 aldehyde dehydrogenase gene. Yeast 19, 295-301.

Ganter, P.F. and de Barros Lopes, M. (2000) The use of anonymous DNA markers in assessing worldwide relatedness in the yeast species Pichia kluyveri Bedford and Kudrjavzev. Canadian Journal of Microbiology 46, 967-980.

Yap, N.A., de Barros Lopes, M., Langridge, P. and Henschke, P.A. (2000) The incidence of killer activity of non-Saccharomyces yeasts towards indigenous yeast species of grape must: potential application in wine fermentation. Journal of Applied Microbiology 89, 381-389.

de Barros Lopes, M., Rehman A.-U., Gockowiak, H., Heinrich, A.J., Langridge, P. and Henschke, P.A. (2000) Fermentation properties of a wine yeast over-expressing the Saccharomyces cerevisiae glycerol 3-phosphate dehydrogenase gene (GPD2). Australian Journal of Grape and Wine Research 6, 208-215.

de Barros Lopes, M., Rainieri, S., Henschke, P.A. and Langridge, P. (1999) AFLP fingerprinting for analysis of yeast genetic variation. International Journal of Systematic Bacteriology 49, 915-924.

de Barros Lopes, M. Soden, A., Martens, A.L., Henschke, P.A. and Langridge, P. (1998) Differentiation and species identification of yeasts using PCR. International Journal of Systematic Bacteriology 48, 279-286.

de Barros Lopes, M., Soden, A., Henschke, P.A. and Langridge, P. (1996) PCR differentiation of commercial yeast strains using intron splice primers. Applied and Environmental Microbiology 62, 4514-4520.

Stone, D.E., Cole, G.M., de Barros Lopes, M., Goebl, M. and Reed, S.I. (1991) N-myristoylation is required for function of the pheromone-responsive G alpha protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase. Genes and Development 5, 1969-1981.

de Barros Lopes, M., Ho J.Y. and Reed, S.I. (1990) Mutations in cell division cycle genes CDC36 and CDC39 activate the Saccharomyces cerevisiae mating pheromone response pathway. Molecular and Cellular Biology 10, 2966-2972.

Hadwiger, J.A., Wittenberg, C., Richardson, H.E., de Barros Lopes, M. and Reed, S.I. (1989) A family of cyclin homologs that control the G1 phase in yeast. Proceedings of the National Academy of Sciences, USA 86, 6255-6259.

Reed, S.I. M.A. de Barros Lopes, J. Ferguson, J.A. Hadwiger, J.-Y. Ho, R. Horwitz, C.A. Jone, A.T. Lörincz, M.D. Mendenhall, T.A. Peterson, S. Richardson and C. Wittenberg (1985). Genetic and Molecular Analysis of Division Control in Yeast, Cold Spring Harbor Symp. Quant. Biol., 50:627-634